Influence of azelnidipine or Amlodipine on renal function and renin-angiotensin-aldosterone systemafter cardiac surgery

Influence of azelnidipine or Amlodipine on renal function and renin-angiotensin-aldosterone systemafter cardiac surgery - nfluence of azelnidipine or Amlodipine on renal function and renin-angiotensin-aldosterone systemafter cardiac surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001638

Enrollment

100

Registered

2009-01-15

Start date

2008-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myocardial infarction, angina, valve disease, aortic dissection

Interventions

azelnidipine group: azelnidipine 16mg amlodipine group: amlodipine5mg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient undergoing cardiac surgery Patient from whom informed consent was obtained

Exclusion criteria

Exclusion criteria: hypotension

Design outcomes

Primary

Measure	Time frame
eGFR	—

Secondary

Measure	Time frame
blood pressure, heart rate, renin, angiotensin-II, aldsterone	—

Countries

Japan

Contacts

Public ContactAkira Sezai

Nihon University school of medicine Department of Cardiovascular Surgery

asezai.med@gmail.com03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026