Neoadjuvant chemoradiotherapy followed by esophagectomy for REG I positive T4, N4 or many thoracic esophageal cancer

Neoadjuvant chemoradiotherapy followed by esophagectomy for REG I positive T4, N4 or many thoracic esophageal cancer - Neoadjuvant chemoradiotherapy followed by esophagectomy for REG I positive T4, N4 or many thoracic esophageal cancer

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001626

Enrollment

Registered

2009-01-07

Start date

2009-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thoracic esophageal cancer

Interventions

esophagectomy with lymph nodes dissection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) primary squamous cell carcinoma of thoracic esophagus (2) clinical-T4, clinical-N4 or N-many (3) ECOG-PS 0,1,2 (4) resectable esophageal cancer (5) Cr<1.2 mg/dl, BUN<25 mg/dl, 24h CCr>60 ml/min, T.Bil<1.2 mg/dl, GOT and GPT<100 IU, WBC>4,000 /mm3, Hb>10 g/dl, Plt>100,000 /mm3, PaO2>70 torr

Exclusion criteria

Exclusion criteria: (1) treatment history of chemotherapy or radiotherapy

Design outcomes

Primary

Measure	Time frame
overall survival	—

Countries

Japan

Contacts

Public ContactSatoru Motoyama

Akita University School of Medicine Department of General Affairs

soumu@hos.akita-u.ac.jp018-834-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026