Effect of ghrelin on airway inflammation in patients with chronic lower respiratory infection

Effect of ghrelin on airway inflammation in patients with chronic lower respiratory infection - Effect of ghrelin on airway inflammation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001598

Enrollment

Registered

2009-01-05

Start date

2008-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic lower respiratory infection

Interventions

Human ghrelin (2microgram/kg, 20 mL solution) was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously. After one week interval

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) persistent productive cough with purulent sputum for >6 months 2) isolation of multidrug-resistant pathogens from sputum 3) BMI<21kg/m2

Exclusion criteria

Exclusion criteria: 1) patients with diabetes mellitus, severe cardiac disease, hepatic disease, renal insufficiency 2) pregnant women 3) patients with infections in other organs than the lungs

Design outcomes

Primary

Measure	Time frame
volume of sputum	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026