comparison of target-controlled and manually-controlled infusion of remifentanil for conscious sedation of awake nasotracheal fiberoptic intubation in patients with maxillofacial surgeries and suspected cervical injurey

comparison of target-controlled and manually-controlled infusion of remifentanil for conscious sedation of awake nasotracheal fiberoptic intubation in patients with maxillofacial surgeries and suspected cervical injurey - comparison of target controlled and manually controllef infusion of remifentanil

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001586

Enrollment

Registered

2008-12-30

Start date

2008-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

traumatic injured patients who need nasotracheal intubation for elective maxillofacial surgery and have documented or suspected cervical spinal injurey

Interventions

In group A :target controlled infusion of remifentanil with TCI pump and effect site target concentration of 0.8ng/ml and 0.2 ng incremental target if needed.the goals of infusion are analgesia durin

8/min),and acceptable consciousness (OAA/S equal or more than 3). In group B: remifentanil loading dose of 0.75 mic/kg body weight over 30 s, followed by a continous infusion 0.075 mic/kg/min.The goal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA class I-III patients who need nasotracheal intubation for elective maxillofacial surgery and have documented or suspected cervical spinal injurey in which any neck movement is considered a risk.

Exclusion criteria

Exclusion criteria: history of drug abuse, long term use of sedatives such as benzodiazepines, uncontrolled hypertensive disease.

Design outcomes

Primary

Measure	Time frame
vital signs during procedure,analgesia and intubation condition	—

Countries

Asia(except Japan)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026