Effects of baclofen on body weight in obese patients

Effects of baclofen on body weight in obese patients - Effects of baclofen on obesity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001573

Enrollment

Registered

2008-12-15

Start date

2008-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity

Interventions

All patients will be administered baclofen (three times a day) for 12 weeks. The amount of baclofen is 15 mg/day for day1-3, 20 mg/day for day 4-6, 25 mg/day for day 7-9, and 30 mg/day for day 10-84

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: BMI: 30 or more

Exclusion criteria

Exclusion criteria: patients with renal failure (Cr 1.5 mg/dl or more), insulin therapy, pregnancy or possible pregnancy, epilepsy (including its past history), mental diseases, ulcer or respiratoy failure patients who have been taking sleeping pills patients who the doctor judges should not be involved in the study

Design outcomes

Primary

Measure	Time frame
body weight, waist size	—

Secondary

Measure	Time frame
parameters related to glucose and lipid metabolism, blood pressure, appetite	—

Countries

Japan

Contacts

Public ContactHiroshi Arima

Nagoya University Graduate School of Medicine Department of Endocrinology and Diabetes

arima105@med.nagoya-u.ac.jp052-744-2142

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026