Small bowel mucosal injury
Conditions
Interventions
Lactobacillus casei
no treatment
Sponsors
Gastroenterology Division, Yokohama City University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: a. The patients who have taken low-dose aspirin for more than three months and who will take low-dose aspirin for 8 weeks after enrollment. b. Obtaining informed consent
Exclusion criteria
Exclusion criteria: a. The patients with dysphagia. b. Pregnant or lactating women. c. The patients who have history of the ileus or stricture or fistula of the intestine. d. The patients who have Crohn's disease, Behchet's disease. e. The patient with pacemaker or other medical electronic equipment. f. Allergic or idiosyncratic to the drug. g. Useage of misoprostol. h. Useage of NSAIDs or anti-cancer drugs. i. Chronic alcohol consumption. j. A history of abdominal surgery. k. severely ill patients. l. The subject of any other clinical test/trial which will affect the results this study. m. Can not comply with the study requirements or cannot follow instructions for the device. n. Do not agree to remove the capsule either by endoscopically or surgically when retention occurred. o. Inadequate to entry judged by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Capsule endoscopic findings (number of red spots, loss of villi and mucosal breaks) | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of hemoglobin levels Safety | — |
Countries
Japan
Contacts
Public ContactEndo Hiroki
Yokohama City University Graduate School of Medicine Gastroenterology Division
Outcome results
None listed