chronic respiratory failure
Conditions
Interventions
Human ghrelin (1 microgram/kg, 10 mL solution) was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 3 weeks continuously.
Human ghrelin (2 mic
Sponsors
University of Miyazaki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)cachectic patient with chronic respiratory failure (BMI<21kg/m2) 2)the underlying disease, which is chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and/or old tuberculosis, is stable within 2 months prior to the study
Exclusion criteria
Exclusion criteria: 1)patient with cancer (and/or post-operative state), lymphangiomyomatosis, lymphoproliferative disease, collagen lung, neuromuscular disease, primary hypoventilation syndrome, pneumoconiosis, eosinophilic granulomatosis, and/or diffuse panbronchiolitis 2)patient with diabetes mellitus (HbA1c>8.0) 3)patient with severe heart disease 4)patient with liver dysfunction 5)patient with renal dysfunction 6)pregnant woman 7)patient with dementia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-min walking distance | — |
Countries
Japan
Outcome results
None listed