Patients with hypercholesterolemia
Conditions
Interventions
pitavastatin treatment
Sponsors
Hakodate social gathering for atherosclerosis
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who satisfy all the inclusion criteria below. 1)Patients with hypercholesterolemia as defined by any of the following criteria. 1.LDL-C>=140 mg/dL 2.Cholesterol-lowering treatment is necessary in a accordance with the investigator's judgment when patient's LDL-C is between 100 to 140 mg/dL. 2)Patients 20 years or older 3)Male or Female 4)Outpatients 5)Patients giving written consent by their own volition after being provided sufficient explanation for participation in this trial. Patients who satisfy all the inclusion criteria below. 1)Patients with hypercholesterolemia as defined by any of the following criteria. 1.LDL-C>=140 mg/dL 2.Cholesterol-lowering treatment is necessary in a accordance with the investigator's judgment when patient's LDL-C is between 100 to 140 mg/dL. 2) Patients 20 years or older 3) Male or Female 4) Outpatients 5) Patients giving written consent by their own volition after being provided sufficient explanation for participation in this trial. Patients who satisfy all the inclusion criteria below.
Exclusion criteria
Exclusion criteria: 1) Patients who meet contraindication or warning of LIVALO below(1-5). 1.Patients who have hypersensitivity to any component of this medicine. 2. Patients who have severe liver dysfunction or biliary atresia. 3. Patients receiving cyclosporine 4. Patients who are or might be pregnant or are in lactation period. 5. Patients taking fibrates with any abnormalities in clinical data about kidney function. 2) Patients already taking LIVALO. 3) Patients who are ineligible in the opinion of the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of IMT and LINE obtained by carotid ultrasonography at the 12 to 24 months from the baseline. Changes of PWV at the 12 to 24 months from the baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Co-relation between morphological change of carotid artery and change serum lipids or inflammatory markers. Co-relation between Pulse Wave Velocity (PWV) and biomarkers. | — |
Countries
Japan
Contacts
Public ContactShigeo Nakajima
Nakajima Internal medicine, circulatory system and mental Clini Internal medicine and circulatory system
Outcome results
None listed