Impact of ultrapure dialysate on white blood cells activation in hemodialysis patients

Impact of ultrapure dialysate on white blood cells activation in hemodialysis patients - Ultrapure dialysate and white blood cells activation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001429

Enrollment

Registered

2008-10-15

Start date

2008-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemodialysis

Interventions

ultrapure dialysate conventional dialysate

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Renal dysfunction: end-stage chronic kidney disease, require maintenance dialysis due to renal dysfunction 2) Expected survival time is more than 6 months 3) Aged 20 years over 4) Fully informed consent was obtained

Exclusion criteria

Exclusion criteria: 1) Malignancy 2) Malnutrition 3) Active inflammatory or infectious disease 4)) Abdominal ascites or pleural effusion 5) Pregnancy 6) Judged inappropriate for this study by the physicians

Design outcomes

Primary

Measure	Time frame
Comparison of expression levels of white blood cells (neutrophils and monocytes) surface receptors (TR2, TR4, CD11b, CD14, CD16, CD18), inflammatory factors (cytokone, myeloperoxidase) releasing from those cells between CD and ultrapuredialysate.	—

Secondary

Measure	Time frame
Comparison of serum protein, nutritional state	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026