Esophageal cancer
Conditions
Interventions
Sponsors
The University of Tokyo Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Recurrent or inoperable esophageal cancer patients who meet the following: - Pathological Diagnosed of esophageal cancer ; - Diagnosis of recurrent esophageal cancer by imaging; - Resistant to standard therapy, or resistant to or refuse DCF therapy; - Life-expectancy is more than 3 months; - Performance status is 0-1; - No serious abnormality in heart, lung, bone marrow, liver, and renal functions.
Exclusion criteria
Exclusion criteria: Patients who have: - Pulmonary fibrosis or interstitial pneumonia, including their history or predisposition; - Active enteritis; - Active autoimmune diseases; - Active infections; - Other cancers; - Other serious complications; - Continuous systemic administration of steroids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival Response rate Survival rate (1 and 2 years) Response of tumor-related markers Immunological responses Safety | — |
Countries
Japan
Contacts
Public ContactKazuhiro Kakimi
The University of Tokyo, Graduate School of Medicine Department of Immunotherapeutics
Outcome results
None listed