Peripheral arterial disesase
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with peripheral arterial disease which was established by angiography, MDCT or vascular echo and have intermittend claudication. We don't consider whether patients have a history of revasulization therapy or not. Patients received the education of life style modification.
Exclusion criteria
Exclusion criteria: Patients cannot do treadmill exersize test, for exanmple of CLI(critical limb ischemia). Patients who have severe heart diseases (LV dysfunction (EF less than 35%, severe ischemic heart disease and valvelar heart disease)). Patients who have severe comorbidities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Evaluation of the severity of intermittend claudication 2)ICD(initial claudication distance),ACD(absolute claudication distance) 3)ABI,TBI,PWV 4)QOL(SF36,WIQ score) 5)SPP(skin perfusion pressure) 6)IMT 7)Labo data(WBC,Alb,BUN,Cre,LDL-chol,HDL-chol,TG,UA,High sense CRP,AST,ALT,LDH,T-Bil,CK,HbA1c,BNP,homocysteine,fibrinogen,D-dimer,U-pro,U-micro alb,U-UN,U-Cre) | — |
Countries
Japan