Clinical effect of luekotriene receptor antagonist on provocation symptom induced by Japanese cedar pollene antigen disc and grope for clinical marker of nasal obstraction

Clinical effect of luekotriene receptor antagonist on provocation symptom induced by Japanese cedar pollene antigen disc and grope for clinical marker of nasal obstraction - Clinical effect of luekotriene receptor antagonist for Japanese cedar pollinosis

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001362

Enrollment

Registered

2008-10-01

Start date

2008-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Japanese cedar pollinosis

Interventions

It is given the test capsule containing leukotriene receptor antagonist(montelukast Na 10mg): 1 capsule per 1 day for a week before the Japanese cedar pollene provocation test. It is given the placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: CAP-RAST against Japanese cedar pollen over class 2 whith clinical history of allergic symptoms during the Japanese cedar pollen season.

Exclusion criteria

Exclusion criteria: Pregnancy, potential pregnancy, and breast-feeding patient.

Design outcomes

Secondary

Measure	Time frame
Serum and urinary oxidized stress substances concentration. Nicotid Oxide concentration in nasal cavity	—

Primary

Measure	Time frame
Effect of leukotriene receptor antagonist	—

Countries

Japan

Contacts

Public ContactYouko Osawa

Faculity of Medicine, University of Fukui Dep. of Otorhinolaryngology-Head and Neck Surgery

fukuoka@u-fukui.ac.jp0776-61-3111(ext.2398)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026