Non-small cell lung cancer
Conditions
Interventions
Paclitaxel and carboplatin are given on day1 and day15 every 28days.
Sponsors
Keio University School of Medicine Division of Pulmonary Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients who were histologically or cytologically confirmed non-small cell lung cancer. 2)Patients who have measurable lesion. 3)No prior chemotherapy. 4)Stage IIIB or IV. 5)ECOG PS 0-2 6)Older than 70years old. 7)Patients who have adequate organ function. WBC>=4000/mm3 neutrophil count>=2000/mm3 Platelet count>=100,000/mm3 Hemoglobin>=9.0g/dl GOT,GPT within twice the upper limit of normal of institution Serum creatinine <=1.5mg/dl Normal ECG or UCG 8)Patients who have no severe complication. 9)Patients who have estimated life expectancy longer than 1 month. 10)Written informed consent.
Exclusion criteria
Exclusion criteria: 1)Patients with severe heart disease. 2)Patients with recent history of myocardial infarction. 3)Patients with liver cirrhosis. 4)Patients with pulmonary fibrosis or interstitial pneumonitis with symptoms or apparent abnormalities on chest X-ray. 5)Patients with severe diabetis mellitus. 6)Patients with ileus. 7)Patients with infection. 8)Patients with severe complications. 9)Patients with peripheral neuropathy. 10)Patients with severe mental disorder. 11)Patients with severe drug allergy. 12)Patients judged unfit to be enrolled in the study by the investigator .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response Rate | — |
Countries
Japan
Outcome results
None listed