malnutrition
Conditions
Interventions
Enteral formula with lactoferrin and nucleic acids (immune-enhancing enteral formula)
Enteral formula without lactoferrin and nucleic acids
Sponsors
Morinaga Milk Industry Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with serum albumin level between 2.5 and 3.5 g/dL. 2) Patients whose nutrition has come completely from enteral feeding for at least one month. 3) Patients who are expected to continue enteral feeding during the study period. 4) Patients with life expectancy of at least 6 months.
Exclusion criteria
Exclusion criteria: 1) Patients with co-morbid diseases which might affect evaluation of study, such as infectious disease. 2) Patients on artificial dialysis. 3) Patients allergic to milk, soybeans, wheat, or fish oil. 4) Patients participating in other clinical trials. 5) Patients who are judged inappropriate for the study by the physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Natural killer cell activity, phagocytic and sterilizing activity of neutrophils, high sensitive C-reactive protein, albumin, prealbumin | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight, fever from infectious disease, arm circumference, triceps skinfold thickness, calf circumference | — |
Countries
Japan
Contacts
Public ContactYoshiaki Takeuchi
Showa University, School of Medicine Department of Gastroenterology
Outcome results
None listed