Emphysematous lung disease
Conditions
Interventions
Transbronchial autologous blood injection
Sponsors
NDMC COPD Research Group
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with emphysematous lung disease, showing dyspnea on exertion (Medical Research Council: more than Grade 3) despite of optical medical therapy more than for 3 months. 2) CT showing eligible heterogeneous emphysema. 3) Pulmonary function test showing obstructive pattern and air-trapping. 4) Good major organ fnction. 5) Written informed consent.
Exclusion criteria
Exclusion criteria: 1) Evidence of active infection. 2) Evidence of systemic diseases or neoplasia expected to compromise survival during 5-yr period. 3) Any disease or condition that interferes with completion of initial or follow-up assessments. 4) Patients who are judged by the principal or other investigators to be not eligible for enrollment in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of adverse events/ Changes of symptomatic relief assessed by dyspnea scale/ Changes of pulmonary physiological parameters | — |
Countries
Japan
Outcome results
None listed