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Prospective randomized controlled trial of oral sodium phosphate and polyethylene glycol lavage in bowel preparation for colonoscopy

Prospective randomized controlled trial of oral sodium phosphate and polyethylene glycol lavage in bowel preparation for colonoscopy - VisiN study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000001303
Enrollment
200
Registered
2008-08-07
Start date
2008-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients scheduled for colonoscopy

Interventions

Niflec(polyethylene glycol lavage) group 1) 10ml Laxoberon Solution is administered orally at bedtime 2) Patients are instructed to drink only clear liquids after dinner 3) At our endscopy unit, pa

Sponsors

Department of Gastroenterology, The University of Tokyo Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who fills everything the following 1) Patients scheduled for colonoscopy in our hospital 2) Age of patients is from 20 to 75 years old 3) Patients who were able to provide written informed consent for participation in this study 4) Outpatient and in-patient

Exclusion criteria

Exclusion criteria: The following proceduresis excluded from the criteria 1) Patients with uncontrolled congestive heart failure, unstable angina, untreated cardiac arrhythmia, prolong QT interval, myocardial infarction, percutaneous transluminal coronary angioplasty or previous coronary artery bypass graft surgery, basic heart disease (valvular disease, cardiomyopathy, and arrhythmia, etc.) 2) Patients with the presence of ascites 3) Patients with acute bowel obstruction or pseudo-obstruction of the bowel 4) Patients with toxic megacolon 5) Patients with biopsy-proven acute phosphate nephropathy 6) Patients who is known allergy or hypersensitivity to NaP salts or PEG 7) Patients with renal insufficiency (creatinine>2.0mg/dL or BUN>25mg/dL) 8) Patients with a history of convulsive attack or Patients at higher risk of convulsive attack 9) Patients with severe chronic constipation 10) Patients with clinical symptoms caused by narrowing of colon lumen or diverticulosis of colon 11) Patients who need emergency colonoscopy 12) Patients with inflammatory bowel disease 13) Pregnant females and lactating women 14) Patients who needs endoscopic therapy (EMR, polypectomy, etc.) 15) Patients who have past history of abdominal surgery other than appendectomy 16) Patients whom examination the responsible(contributory) doctor evaluate inappropriate as study subjects

Design outcomes

Primary

MeasureTime frame
To evaluate detection rates of polyps smaller than 5mm

Secondary

MeasureTime frame
To evaluate detection rates of all prominent lesions and diverticula To evaluate blood pressure and pulse rates of patients before and after colonoscopy

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026