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Secondary Prevention of Cerebral Infarction Epidemiological Study on Cerebral Microbleeds

Secondary Prevention of Cerebral Infarction Epidemiological Study on Cerebral Microbleeds - SCIENCE Study

Status
Unknown
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000001230
Enrollment
4000
Registered
2008-07-02
Start date
2008-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral infaction

Interventions

None listed

Sponsors

SCIENCE Study Protocol Comittee
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: first onset symptomatic cerebral infarction within 2 months after onset primary treated by each hospital registered MRI acceptable mRS Grade0-4 3-year follow up executable prior written informed consent

Exclusion criteria

Exclusion criteria: recurred symptomatic cerebral infarction medicatin of antiplatelet drugs before onset moyamoya disease, AVM, AN, dural AVF previous cerebral contusion previous craniotomy and/or burr hole surgery future surgery and/or intervention for brain and heart previous symptomatic cerebral hemorrhage, other hemorrhagic disease, coagulopathy present malignancy platelet count<10000/m3 liver dysfunction (AST>100IU/L, ALT>100IU/L) renal dysfunction (Cre>3mg/dl) future moving, diffculties for follow-up amyloid angiopathy participants in other intervening clinical research

Design outcomes

Primary

MeasureTime frame
symptomatic cerebral infarction and symptomatic cerebral hemorrhage

Secondary

MeasureTime frame
number of cerebral microbleeds, Grade of DWMH and PVH, ADL, event by antiplatelet drugs, symptom of upper GI and QOL, other cerebrovascular event, cardiovascular event, death

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026