Elevation of uterine basal tone after combined spinal epidural or epidural labor analgesia and its association with fetal heart rate abnormalities: a randomized double-blind study

Elevation of uterine basal tone after combined spinal epidural or epidural labor analgesia and its association with fetal heart rate abnormalities: a randomized double-blind study - Uterine hyperactivity and fetal heart rate abnormalities after combined spinal epidural or epidural analgesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001193

Enrollment

Registered

2008-06-17

Start date

2006-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fetal heart rate abnormalities occurring after labor analgesia

Interventions

combined spinal epidural analgesia with initial intrahecal injection of bupivacaine 2,5 mg with 2,5 mcg sufentanil epidural analgesia with initial epidural injection of bupivacaine 12,5mg with 10 mcg

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: laboring patients in active phase of labor who asked for labor analgesia

Exclusion criteria

Exclusion criteria: contraindications to internal monitoring of uterine contractions, contraindications to regional analgesia, previous use of opiates for pain relief during labour

Design outcomes

Primary

Measure	Time frame
Occurrence of elevation of uterine basal tone associated with nonreassuring fetal rate tracings after labor analgesia	—

Countries

South America

Contacts

Public ContactRossana Pulcineli Vieira Francisco

School of Medicine, University of Sao Paulo , Sao Paulo, Brazil Department of Obstetrics and Gynecology

rossana.francisco@hcnet.usp.br551130696209

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026