Analysis of Rho kinase (ROCK) activity in subjects with cerebrocardiovascular risk factor

Analysis of Rho kinase (ROCK) activity in subjects with cerebrocardiovascular risk factor - ROCK study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001167

Enrollment

1000

Registered

2008-06-01

Start date

2008-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension, Diabetes mellitus, Hyperlipidemia, Cigarette smoking, Coronary heart disease, Cerebrovascular disease, Peripheral artery disease, Arteriosclerosis

Interventions

Antihypertensive agent (amlodipine) Antihypertensive agent (losartan)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects with cerebrocardiovascular disease or their risk factors.

Exclusion criteria

Exclusion criteria: Subjects without informed consent

Design outcomes

Primary

Measure	Time frame
ROCK activity, number of coronary risk factor and morbidity of atherosclerotic disease burden, Endothelial function, number of endothelial progenitor cell,CRP, LV hypertrophy and LV diastolic function.	—

Countries

Japan

Contacts

Public ContactYukihito Higashi

Hiroshima university graduate school of biomedical science Department of cardiovascular physiology and medicine

yhigashi@hiroshima-u.ac.jp082-257-5555

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026