Normal Volunteers
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy normal volunteers who meet all of the following criteria. 1) Age ranging from 20 to 89 at the time of informed consent 2) No remarkable findings in mental state examinations performed within 3 months after obtaining informed consent 3) No remarkable findings for his (her) age in MRI and SPECT examinations performed within 3 months after obtaining informed consent. 4) The participant himself (herself) can provide written informed consent.
Exclusion criteria
Exclusion criteria: 1) Being pregnant or its possibility, or in the lactation period. 2) The history of alcoholism 3) The history of epilepsy 4) The educational period was less than 6 years 5) The history of neuron or psychiatry diseases affecting cognitive function. 6) Severe complications including liver or renal dysfunction, endocrine diseases etc. 7) Taking drugs affecting brain perfusion or cognitive function 8) Abnormal findings in MRI including brain atrophy, ischenmia,infarction, etc. 9) The presence of arachnoid cysts 10) Heavy smokers (more than 20 cigarettes per day for more than 20 years).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Normal database of brain perfusion SPECT obtained from normal volunteers whose cognitive function and image findings are judged normal | — |
Countries
Japan
Contacts
School of Medicine, Keio University Department of Radiology