A prospective observation study concerning the incidence of atherothrombotic events in patients with acute coronary syndrome.

A prospective observation study concerning the incidence of atherothrombotic events in patients with acute coronary syndrome. - Prevention of atherothrombotic incidents following ischemic coronary attack (PACIFIC) Registry

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000001128

Enrollment

4000

Registered

2008-05-10

Start date

2008-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute coronary syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inpatients with ACS below: 1) Acute ST-segment elevation myocardial infarction 2) Acute non-ST-segment elevation myocardial infarction 3) Unstable angina pectoris

Exclusion criteria

Exclusion criteria: Patients meeting any of the following criteria will be excluded from the study. 1) Chest pain and coronary diseases developed in association with other serious diseases or their treatments (e.g.: myocardial infarctions associated with car accidents, traumas, serious gastrointestinal hemorrhage or associated with vascular intervention or coronary bypass surgery) 2) Inpatients not intended for close examination/treatment of chest pain 3) Patients who are sub acute stent-thrombosis 4) Patients aged less than 20 years 5) Patients not providing a written consent by themselves or their family members 6) Patients who are disqualified the study by the investigators

Design outcomes

Primary

Measure	Time frame
The incidence of major adverse cardiovascular /cerebrovascular events (MACCE), including vascular death, MI, stroke since baseline to 2 years.	—

Secondary

Measure	Time frame
The incidence of the primary endpoint and each following event are evaluated and the differences of each high-risk patient sub-group are examined. A) Death due to MI B) Death due to stroke C) Other cardiovascular death D) Non-cardiovascular death E) Non-fatal MI, unstable angina F) Non-fatal stroke G) Acute arterial occlusion H) Central retinal artery occlusion I) Coronary revascularization due to myocardial ischemia J) Hospitalization due to HF K) Hospitalization due to TIA L) Hospitalization due to revascularization M) Hemorrhages requiring hospitalization or blood transfusion N) Other adverse events requiring hospitalization O) Target Vessel Failure	—

Measure

Time frame

The incidence of the primary endpoint and each following event are evaluated and the differences of each high-risk patient sub-group are examined. A) Death due to MI B) Death due to stroke C) Other cardiovascular death D) Non-cardiovascular death E) Non-fatal MI, unstable angina F) Non-fatal stroke G) Acute arterial occlusion H) Central retinal artery occlusion I) Coronary revascularization due to myocardial ischemia J) Hospitalization due to HF K) Hospitalization due to TIA L) Hospitalization due to revascularization M) Hemorrhages requiring hospitalization or blood transfusion N) Other adverse events requiring hospitalization O) Target Vessel Failure

—

Countries

Japan

Outcome results