hepatoblastoma hepatocellular carcinoma
Conditions
Interventions
None listed
Sponsors
Japanese Study Group for Pediatric Liver Tumors
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. A child between 6 months and 5 years of age has liver tumors detected by imaging and shows an abnormally high level of serum AFP.(Note, however, that it is necessary to exclude the metastatic liver tumor by totally diagnostic imaging. In addition, when chemotherapy will be performed ahead, pathological diagnosis by biposy is preferable to be done for accurate diagnosis.) 2. A child under 6 months or more 5 years of age had intrahepatic tumor which was diagnosed by pathology. 3 In cases with liver tumor whose serum AFP is normal level, pathological diagnosis by biopsy is obtained regardless of age.
Exclusion criteria
Exclusion criteria: Note that, even if an intrahepatic tumor, the benign liver tumor, hepatocellular carcinoma, and metastatic liver tumors should be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of tumor reduction Improvement of event-free and overall survivals Safety | — |
Secondary
| Measure | Time frame |
|---|---|
| Pancytopenia Digestive organ dysfunction Late complications (cardiac dysfunction, growth disorder, hearing disorder) | — |
Countries
Japan
Contacts
Public ContactSho Kurihara
Hiroshima university hospital Pediatric Surgery
Outcome results
None listed