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Effect of insulin sensitizer treatment on carotid arterial elasticity

Effect of insulin sensitizer treatment on carotid arterial elasticity - PBS(Pioglitazone and Biguanide Study)

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000001085
Enrollment
50
Registered
2008-03-20
Start date
2007-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type2 diabetes

Interventions

Pioglitazone 15mg daily Metformin 750mg daily

Sponsors

Tohoku University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: type 2 diabetes

Exclusion criteria

Exclusion criteria: severe renal dysfunction severe liver dysfunction heart failure history of lactic acidosis severe retinopathy severe vascular disease with urgent treatment HbA1c over 9% blood pressure over 180/100 mmHg

Design outcomes

Primary

MeasureTime frame
change of carotid arterial elasticity—

Secondary

MeasureTime frame
changes of serum markers of atheroscrerosis,pulse wave velocity and carotid intima-media thickness—

Countries

Japan

Contacts

Public ContactYasushi Ishigaki

Tohoku University Graduate School of Medicine Division of Molecular Metabolism and Diabetes

yishigaki@mail.tains.tohoku.ac.jp022-717-7611

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026