Effect of an H2 receptor antagonist or a proton pump inhibitor on prevention of bleeding and healing of the endoscopic submucosal dissection-induced ulceration :a prospective randomized controlled trial

Effect of an H2 receptor antagonist or a proton pump inhibitor on prevention of bleeding and healing of the endoscopic submucosal dissection-induced ulceration :a prospective randomized controlled trial - Effect of an H2 receptor antagonist or a proton pump inhibitor on prevention of bleeding and healing of the endoscopic submucosal dissection-induced ulceration :a prospective randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001069

Enrollment

120

Registered

2008-03-10

Start date

2008-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early gastric cancer,gastric adenoma

Interventions

Administration of H2RA(Roxatidine acetate hydrochloride) for ESD-induced ulcer Administration of PPI (Lansoprazole) for ESD-induced ulcer

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who were diagnosed as early gastric cancer or gastric adenoma and are considered as the indication of endoscopic submucosal dissection.

Exclusion criteria

Exclusion criteria: Patients who have anticoagulant or antiplatelet therapy and who cannot stop it.

Design outcomes

Primary

Measure	Time frame
Bleeding and healing rario after ESD.	—

Countries

Japan

Contacts

Public ContactNaoki Hosoe, M.D., Ph.D.

Keio University Division of Gastroenterology,Department of Internal Medicine

hosenao@db3.so-net.ne.jp03-3353-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026