A prospective, multicentre, observational trial for hemodynamic reaction following initial fluid resuscitation in patients with hemorrhagic shock due to blunt trauma

A prospective, multicentre, observational trial for hemodynamic reaction following initial fluid resuscitation in patients with hemorrhagic shock due to blunt trauma - Hemodynamic reaction following initial fluid resuscitation in patients with hemorrhagic shock

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000001059

Enrollment

100

Registered

2008-03-07

Start date

2007-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma patients with hemorrhagic shock

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients who received initial fluid resuscitation for hemorrhagic shock (2) Patients with physiological abnormality (Step 1), anatomical abnormality (Step 2), or mechanism of injury (high-energy injuries: Step 3) defined by JATEC (guideline p233). Patients who meet criteria for 1 or 2 above.

Exclusion criteria

Exclusion criteria: (1) Penetrating trauma (2) When the physician selected permissive hypotension therapy (3) Cardiopulmonary arrest (4) Patients whose fluid therapy started before admission (5) Patients with terminal stage of chronic disease (6) When the physician consider that the initial fluid resuscitation therapy is inappropriate for the patient (state the specific reason)

Design outcomes

Primary

Measure	Time frame
1) Character of patients with hemorrhagic shock 2) Systolic blood pressure (SBP) and heart rate (HR) on admission 3) SBP and HR at the time when 1L of fluid replacement was administered. 4) SBP and HR at the time when 2L was administered. 5) SBP and HR at the time when the management of ER was finished. 6) Total volume of fluid replacement and blood transfusion at ER 7) Total volume of fluid replacement and blood transfusion during 24 hr 8) Details of interventional treatment performed for hemorrhage	—

Measure

Time frame

1) Character of patients with hemorrhagic shock 2) Systolic blood pressure (SBP) and heart rate (HR) on admission 3) SBP and HR at the time when 1L of fluid replacement was administered. 4) SBP and HR at the time when 2L was administered. 5) SBP and HR at the time when the management of ER was finished. 6) Total volume of fluid replacement and blood transfusion at ER 7) Total volume of fluid replacement and blood transfusion during 24 hr 8) Details of interventional treatment performed for hemorrhage

—

Countries

Japan

Contacts

Public ContactAkiyoshi Hagiwara

National Defense Medical College, Japan Department of Traumatology and Critical Care Medicine

boeihagi@ndmc.ac.jp04-2995-1511

Outcome results