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Primary Hyperaldosteronism in Japan

Primary Hyperaldosteronism in Japan - PHAS-J

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000000998
Enrollment
3500
Registered
2008-02-01
Start date
2005-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

None listed

Sponsors

National Hospital Organization
Lead Sponsor
Cooperative research group for PHAS-J Study of National Hospital Organization
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Hypertensive patients in the outpatient clinic and hospital, who full-fill the following 1) or 2) criteria: 1)treated hypertensive patients 2)untreated hypertensive patients with systolic blood pressure higher than 140mmHg or diastolic blood pressure higher than 90mmHg according to the guideline of the Japan Society of Hypertension.

Exclusion criteria

Exclusion criteria: 1)pregnant patients 2)patients taking diuretics or aldosterone antagonist 3)patients with the following diseases: (1)secondary hypertension (renal hypertension,renovascular hypertension, primary aldosteronism, Cushing's syndrome, pheochromocytoma, iatrogenic diseases etc) (2)patients whom the attending doctors decides not suitable for the entry because of the unstable stage of the following complications: coronary diseases, arrhythmia, severe valvular diseases, cerebrovascular diseases, acute and chronic renal failure (serum Cr higher than 3mg/dl), acute and chronic liver diseases (3)orthostatic hypotension 4) Patients whom the attending doctor decides not suitable for the entry of the study.

Design outcomes

Primary

MeasureTime frame
Prevalence of primary aldosteronism in patients with hypertension in Japan

Secondary

MeasureTime frame
Secondary outcomes are to establish the importance of investigating the cause of hypertension in clinical practice and to spread the standard medical practice specific to the cause of hypertension.

Countries

Japan

Contacts

Public ContactMitsuhide Naruse

National Hospital Organization, Kyoto Medical Center Department of Endocrinology, Clinical Research Institute for Endocrine and Metabolic Diseases

mnaruse@kyotolan.hosp.go.jp075-641-9161

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026