An early phase II study of delayed local treatment with surgery and radiation, that follows high dose chemotherapy with peripheral blood stem cell transplantation in patients with advanced neuroblastoma

An early phase II study of delayed local treatment with surgery and radiation, that follows high dose chemotherapy with peripheral blood stem cell transplantation in patients with advanced neuroblastoma - An early phase II study of delayed local treatment in advanced neuroblastoma

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000973

Enrollment

Registered

2008-01-07

Start date

2005-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuroblastoma

Interventions

Chemothrapy, surgery and radiation in INSS satge 4 neuroblastoma

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Childen older than 1 year with INSS stage 4 neuroblastoma

Exclusion criteria

Exclusion criteria: Active double cancer; pregnant or possiblly pregnant women and those during breast feeding; patients with psychologic disease or symptoms who have difficulty in receiving protocol treatment; patients with disease that may interfere with the protocol treatment

Design outcomes

Primary

Measure	Time frame
1-year progression-free survival rate from the 12th week of the protocol	—

Secondary

Measure	Time frame
2-year progression-free and overall survival rates, clinical response rate at the 12th week of the protocol and that before surgery, the incidence of adverse events	—

Countries

Japan

Contacts

Public ContactHiroyuki Shichino

Nihon University School Of Medicine Division of Pediatrics and Child Health

shichino.hiroyuki@nihon-u.ac.jp0339728111(2442)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026