Analysis of risk factors and prognostic factors included histological status of underlying liver disease of patients undergoing curative resection or radiofrequency ablation of hepatocellular carcinoma; May hepatic steatosis correlate with the postoperative recurrence of hepatocellular carcinoma?

Analysis of risk factors and prognostic factors included histological status of underlying liver disease of patients undergoing curative resection or radiofrequency ablation of hepatocellular carcinoma; May hepatic steatosis correlate with the postoperative recurrence of hepatocellular carcinoma? - Risk and Prognostic factors included hepatic steatosis of HCC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000000970

Enrollment

400

Registered

2008-02-01

Start date

2004-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with Hepatocellular carcinoma(HCC) after curative treatment

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: a)HCC without prior treatments b)Patients underwent curative resection or radiofrequency ablation therapy(RFA) of HCC. Resection was defined as curative when the entire tumor was macroscopically removed and the surgical margin was microscopically free from tumor invasion. c)For patients with HCC the Milan criteria were applied (solitary tumor of 5 cm, or three or fewer lesions, none >3 cm without vascular invasion, or extrahepatic metastasis).

Exclusion criteria

Exclusion criteria: a)Recurred HCC b)uncontrolled other malignancies c)ruptured HCC d)Operation-related death e)Judged to be inadequate case of this clinical study for other reasons by doctors

Design outcomes

Primary

Measure	Time frame
The cumulative tumor recurrence rate in patients with HCC	—

Secondary

Measure	Time frame
Cumulative survival rate in patients with HCC. Risk factors of recurrence of HCC and prognostic factors(these histological findings such as liver steatosis, liver fibrosis, and inflammation, Cancer Stage, Child-Pugh,and laboratory data, etc.)	—

Countries

Japan

Outcome results