Impared Glucose Tolerance
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: We screened for patients aged between 20 and 70 years, BMI: 20&#8211;34 kg/m2, fasting plasma glucose concentration &#8805;100 mg/dl (5.6 mmol/l), or HbA1c level between 5.2 and 6.4%. The patients were eligible for our study if they had impaired glucose tolerance &#8211; defined as plasma glucose concentration &#8804; 125 mg/dl (6.9 mmol/l) in the fasting state, and 140 to 199 mg/dl (7.8 to 11.0 mmol/l) two hours after a 75 g oral glucose load, according to the 2003 ADA criteria. In addition, all participants were confirmed to have systolic blood pressure <150mmHg, diastolic blood pressure <100mmHg, total cholesterol <300mg/dl, triglycerides <220mg/dl, and LDL-cholesterol <180mg/dl.
Exclusion criteria
Exclusion criteria: We exclude patients who were diabetes, hypertension, or hyperlipidemia with taking any medication which might affect glycemic control.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All participants were seen at 3-month intervals by their physicians. Blood and urine samples were taken for examination. We estimated the incidence of type 2 diabetes. | — |
Secondary
| Measure | Time frame |
|---|---|
| All participants were seen at 3-month intervals by their physicians. Body weight, waist circumference, and blood pressure were measured. We estimated the efficay of our program for changes in serum lipids, body weight, and blood pressure | — |
Countries
Japan
Contacts
Niigata-Rousai Hospital, Joetsu, Japan Department of Internal Medicine