Huntington'
Conditions
Interventions
Step1 To take Chai hu jia long gu mu li tang 56 days Step2 Wash out 28 days Step3 To take Yigan San 56 days
Step1 To take Yigan San 56 days Step2 Wash out 28 days Step3 To take Chai hu jia long gu
Sponsors
Yonezawa National Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Clinically diagnosed as Huntington's disease according to ICD10 with abnormal prolongation of CAG repeat in IT15 gene. 2.At least one subscore of UHDRS is more than 3. 3.Serum potassium level is within the normal limit. 4.Stayed in the hospital over 5 years 5.A single care giver takes care each patient.
Exclusion criteria
Exclusion criteria: 1.with any malignancy 2.with severe heart disease, liver disease, blood disease, respiratory disease and any other severe diseases influenced on the patients states 3.With any neurodegenerating diseases other than Huntington's disease 4.Alcohol abuse, drug abuse, metabolic toxicity, chronic inflammatory diseases 5.Who can not take herbal medicine per os. 6.Who are perscribed any antipsychotics newly in the observation period. 7. Others who are judged as inadequate by attending doctors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unified Huntington's Disease Rating Scale (UHDRS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function, ADL, Use of rescue drug, toralance | — |
Countries
Japan
Contacts
Public ContactKoh Iwasaki
Graduate School of Medicine, Tohoku University Center for Asian Traditional Medicine
Outcome results
None listed