Curative distal gastrectomy for gastric cancers
Conditions
Interventions
Billroth-I method
Roux-en-Y method
Sponsors
Clinical surgery research group/The supporting center for clinilcal and education
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Primary treatment for histologically proven adenocarcinoma of the stomach. 2)Indication for distal gastrectomy due to tumor localization 3) Reconstruction feasible for both Billroth I and Roux-en-Y 4) Aged 20 to 90 years old 5) PS (ECOG) of 0 or 16) Curable operation ( Curability B or more according to Japanese Classification for Gastric carcinomas) 7) Written informed consent
Exclusion criteria
Exclusion criteria: 1) History of laparotomy excluding laparoscopic cholecyctectomy and addendectomy (skin incision less than 5cm) 2) Non-curative factors proven by pre-operative examinations 3) Pre-operatiev chemotherapy 4) Synchronous malignancies other than carcinoma in situ of cervical cancer or focal cancer in adenoma of colorectal cancers 5) Metachronous malignancies within 5 years or with tumor recurrence 6) Severe respiratory dysfunction 7) History of myocardial infarction of two-step Master positive by ECG 8) Liver cirrhosis or chronic active hepatitis 9) Chronic renal failure with hemodialysis 10) Uncontrolled diabetes (HbA1C 9.0 or more) 11) Reflux esophagitis (LA grade A or more) 12) Other unfeasible factors to perform study safely, approved by attending surgeon
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body weight loss rate at one year afer surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of delayed gastric empty, reflux esphagitis and surgical complication | — |
Countries
Japan
Contacts
Public ContactYuichiro Doki, MD
Osaka University, Graduate School of Medicine Gastroenterological Surgery
Outcome results
None listed