Patients at high-risk for coronary artery disease
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients at high risk for CAD. High risk for CAD was defined as having more than 2 factors of following; age 65 years or older; current smoking; hypertension (140/90 mmHg or more, or taking any antihypertensive medications); dyslipidemia (high density lipoprotein [HDL] cholesterol less than 40mg/dl, low-density lipoprotein [LDL] cholesterol 140mg/dl or more, or triglycerides 150mg/dl or more); diabetes mellitus; body mass index (BMI) 25.0 kg/m2 or more; family history of ischemic heart disease. Patient with stable CAD or history of old myocardial infarction (OMI) were also enrolled
Exclusion criteria
Exclusion criteria: The exclusion criteria for the study were severe valvular heart disease requiring surgical intervention, plan for coronary revascularization, active infection, and malignant disease. Patients with ACS were also excluded because they had a significantly higher cardiovascular event ratio than that of stable CAD patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The end points were any of cardiovascular death, nonfatal myocardial infarction, unstable angina, fatal or nonfatal ischemic stroke, or coronary revascularization to new lesions. | — |
Countries
Japan
Contacts
Graduate School of Medical Sciences, Kumamoto University Department of Cardiovascular Medicine