Randomized study of 21-gauge vs. 22-gauge endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) needles for sampling mediastinal and hilar lesions

Randomized study of 21-gauge vs. 22-gauge endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) needles for sampling mediastinal and hilar lesions - Comparison of 21-gauge vs. 22-gauge EBUS-TBNA needles

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000840

Enrollment

Registered

2007-10-01

Start date

2007-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mediastinal or hilar lesions

Interventions

EBUS-TBNA using 21-gauge needle EBUS-TBNA using 22-gauge needle

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with enlarged mediastinal and/or hilar lesions 10 mm or greater in short-axis diameter on CT requiring diagnostic bronchoscopy 2. 20 years old and above 3. Informed consent

Exclusion criteria

Exclusion criteria: 1. Patients with severe concomitant medical illness 2. Patients who were enrolled in other EBUS-TBNA studies 3. Bleeding tendency 4. Pregnant woman 5. Other clinical difficulties in this study

Design outcomes

Primary

Measure	Time frame
1. Yields for adequate histologic specimen retrieval	—

Secondary

Measure	Time frame
1. Yields for adequate cytologic specimen sampling 2. Diagnostic yields 3. Frequency of adverse effects	—

Countries

Japan

Contacts

Public ContactMasahide Oki

Nagoya Medical Center Department of Respiratory Medicine

Masahideo@aol.com

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026