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Studies on the effect of dietary phosphorus loading on the physiological function and determination of tolerable upper intake level of phosphorus in human.

Studies on the effect of dietary phosphorus loading on the physiological function and determination of tolerable upper intake level of phosphorus in human. - Dietary phosphorus loading trial in human.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000000803
Enrollment
30
Registered
2007-08-31
Start date
2008-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease, Cardiovascular disease, metabolic bone disease

Interventions

high phosphorus diet (Phosphorus 1200mg/meal, bolus) -&gt
wash out period (al least 1day) -&gt
control phosphorus diet (Phosphorus 400mg/meal, bolus) control phosphorus diet (Phosphorus 400mg/meal, bolus) -&gt
high phosphorus diet (Phosphorus 1200mg/meal, bolus) high phosphorus diet (Phosphorus 800mg/meal, bolus) -&gt
control phosphorus diet (Phosphorus 400mg/meal, bolus)

Sponsors

Department of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Healthy men, non-smoker Healthy women, non-smoker

Exclusion criteria

Exclusion criteria: hyperlipidemia, hypertension, kidney dysfunction, diabetes, cardiovascular disease

Design outcomes

Primary

MeasureTime frame
Serum P, serum Ca, intact PTH, intact FGF23, urinary P, urinary Ca, Flow-mediated dilation (FMD) before and after the meal ingestion (until 8h later).

Secondary

MeasureTime frame
Serum TG, serum glucose, serum creatinine, urinary creatinine before and after the meal ingestion (until 8h later).

Countries

Japan

Contacts

Public ContactYutaka Taketani

University of Tokushima Graduate School, Institute of Health Biosciences Department of Clinical Nutrition

taketani@nutr.med.tokushima-u.ac.jp088-633-9597

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026