Multifactorial effects of insulin sensitizers

Multifactorial effects of insulin sensitizers - Multifactorial effects of insulin sensitizers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000771

Enrollment

Registered

2007-07-16

Start date

2004-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

pioglitazone metformin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Type 2 diabetic patients with HbA1c levels of 6.5-9.0%

Exclusion criteria

Exclusion criteria: 1. treated with insulin 2. renal dysfunction 3. history of heart failure and cerebrovascular disease 4. liver dysfunction 5. pulmonary dysfunction 6. pregnancy or lactation 7. history of side effects by thiazolidinediones or biguanides 8. judged inappropriate for this study by the physicians

Design outcomes

Primary

Measure	Time frame
Insulin secretion and sensitivity, surrogate markers of atherosclerosis, adipocytokines, and appetite-regulating hormones	—

Countries

Japan

Contacts

Public ContactShoichiro Nagasaka

Jichi Medical University Division of Endocrinology and Metabolism

sngsk@jichi.ac.jp0285-58-7355

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026