BEDTIME ADMINISTRATION OF LONG-ACTING ANTIHYPERTENSIVE DRUGS RESTORES NORMAL NOCTURNAL BLOOD PRESSURE FALL IN NON-DIPPERS WITH ESSENTIAL HYPERTENSION

BEDTIME ADMINISTRATION OF LONG-ACTING ANTIHYPERTENSIVE DRUGS RESTORES NORMAL NOCTURNAL BLOOD PRESSURE FALL IN NON-DIPPERS WITH ESSENTIAL HYPERTENSION - Timed therapy for non-dipper hypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000765

Enrollment

100

Registered

2007-07-13

Start date

2003-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Essential hypertension

Interventions

We studied Japanese adult patients with essential hypertension who had been receiving long-acting antihypertensive drugs once daily in the morning and changed medication time to bedtime in non-dippers

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Japanese adult patients with essential hypertension receiving antihypertensive treatment

Exclusion criteria

Exclusion criteria: Patients with diabetes, renal dysfunction (serum creatinine>1.2 mg/dL), or a history of cardiovascular diseases were excluded

Design outcomes

Primary

Measure	Time frame
the office and 24-hour ambulatory blood pressure, and the percentages of nocturnal decline in blood pressure	—

Countries

Japan

Contacts

Public ContactAtsushi Takeda

Midorino Clinic Director

atakeda@midorino.com0297-30-3311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026