Observational Registry:Gastrointestinal Complications developed during low-dose aspirin intake or atherothrombosis such as myocardial infarction and cerebral infarction-

Observational Registry:Gastrointestinal Complications developed during low-dose aspirin intake or atherothrombosis such as myocardial infarction and cerebral infarction- - Management of Aspirin-induced Gastrointestinal Complications (MAGIC)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000000750

Enrollment

1500

Registered

2007-07-01

Start date

2005-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral infarction, TIA, angina, myocardial infarction, atrial fibrillation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Cerebrovascular disease (cerebral infarction, TIA et al), Coronary heart disease(angina,Myocardial infarction et al), Atrial fibrillation With 1)20 years-old or older, 2) Asprin intake under 330mg as daily dose for 1 month or more, 3) Outpatients

Exclusion criteria

Exclusion criteria: 1) Serious hepatic or renal disorder with treatment required, 2)Serious lung disorder with treatment required, 3)Pregnant, Possible pregnant, Pregnant desired, 4) Uncontrolled DM, 5)Cancer patient with treatment required, 6)Patient experienced surgery for esophagus, stomach, and duodenal disease, 7)Patient having hypersensitivity against aspirin or other salicylic acids, 8)Patient whom the investigator determined as inadequate

Design outcomes

Primary

Measure	Time frame
Findings of ulcer, and erosion in upper GI under endoscopy	—

Secondary

Measure	Time frame
Event rate: GI hemorrhage and alternative LANZA score (stomach), Cerebral hemorrhage, Other systematic hemorrhage, cardiovascular death, nonfatal MI, nonfatal cerebrovascular infarction, TIA, Coronary angioplasty /STENT insertion, worsening of primary disease	—

Countries

Japan

Contacts

Public ContactShinya Goto

Tokai University School of Medicine Department of Medicine

shinichi@is.icc.u-tokai.ac.jp0463-93-1121

Outcome results