Patients undergoing total arch replacement without any additional cardiac procedures.
Conditions
Interventions
Group of 28 deg C : Temperature at bladder should be 28 plus minus 2 deg C, and the perfusion pressure of SCP should be over 50mmHg.
Group of 20 deg C : Temperature at bladder should be 20 plus minus
Sponsors
National Cardiovascular Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients undergoing total arch replacement without any additional cardiac procedures. All operative procedures can be possible through median sternotomy.
Exclusion criteria
Exclusion criteria: 1) Emergency cases 2) Extended aneurysms, i.e., existence of concomitant root, descending, thoracoabdominal, abdominl aneurysms. 3) Patients with severe atheromatous lesion. 4) Atypical aortic diseases, i.e., Takayasu disease, Behcet disease, Marfan syndrome, Ehlers-Danlos syndrome. 5) Severe grade of arteriosclerosis obliterans. 6) Re-sternotomy cases 7) Abnormality of neurological, cardiac, respiratory, hepatic, renal, hematological functions. 8) Infections 9) Cancer-bearing patients. 10) Mental diseases, including dementia. 11) Other improper patients judged by physician-in-charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary parameter for the evaluation of the study is the total volume of transfusion. | — |
Secondary
| Measure | Time frame |
|---|---|
| The other parameters for the evaluation of the study are operative death, neurological complications, cardiac complications, respiratory complications, renal complications, amount of bleeding, and infectious complications. | — |
Countries
Japan
Contacts
Public ContactHitoshi Ogino
National Cardiovascular Center Department of Cardiovascular Surgery
Outcome results
None listed