Effects of renal dysfunction and sleep apnea on ambulatory blood pressure profile, cardiovascular function, and glucose and lipid metabolism: cross-sectional and prognosis study.

Effects of renal dysfunction and sleep apnea on ambulatory blood pressure profile, cardiovascular function, and glucose and lipid metabolism: cross-sectional and prognosis study. - Effects of renal dysfunction and sleep apnea on ambulatory blood pressure profile, cardiovascular function, and glucose and lipid metabolism: cross-sectional and prognosis study.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000000667

Enrollment

500

Registered

2008-11-01

Start date

2005-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensionj

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Blood pressure >= 130/80

Exclusion criteria

Exclusion criteria: acute myocardial infarction, collagen disease, acute renal failure

Design outcomes

Primary

Measure	Time frame
1) casual blood pressure 2) ambulatory blood pressure monitoring 3) sleep apnea test 4) renal function: creatinine clearance by Cockcroft-Gault formula 5) glucose metabolism: fasting blood glucose, fasting IRI, HOMA-IR 6) lipid metabolism: total cholesterol, LDL, HDL, TG, adiponectin 7) cardiac function: ANP, BNP, UCG 8) vascular function: ABI/BWV, carotid echogram 9) sympathetic nerve activity and renin-angiotensin system 10) inflammatory and oxidative markers: CRP, fibrinogen, MDA-LDL, AGE.	—

Measure

Time frame

1) casual blood pressure 2) ambulatory blood pressure monitoring 3) sleep apnea test 4) renal function: creatinine clearance by Cockcroft-Gault formula 5) glucose metabolism: fasting blood glucose, fasting IRI, HOMA-IR 6) lipid metabolism: total cholesterol, LDL, HDL, TG, adiponectin 7) cardiac function: ANP, BNP, UCG 8) vascular function: ABI/BWV, carotid echogram 9) sympathetic nerve activity and renin-angiotensin system 10) inflammatory and oxidative markers: CRP, fibrinogen, MDA-LDL, AGE.

—

Countries

Japan

Contacts

Public ContactKazukai Uchino

Yokohama City University School of Medicine Department of Medical Science

uchinok@med.yokohama-cu.ac.jp045-787-2634

Outcome results