Hyperlipidemia
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with hyperlipidemia without severe complications and who agreed with the study. Both outpatients and in-patients who fulfilled the following criteria: 1) diagnosis of hypercholesterolemia based upon the diagnostic criteria of the Japan Atherosclerosis Society and 2) over the age of 20 years. Those patients who have been treated under the diagnosis of hypercholesterolemia can also be included.
Exclusion criteria
Exclusion criteria: 1) Patients with known thyroid hormone abnormalities 2) Patients with hyperlipidemia due to known diseases other than the thyroid diseases: nephrotic syndrome, primary biliary cirrhosis, obstructive jaundice, Cushing's syndrome, acromegaly, pheochromocytoma, medicine (diuretics, beta blockers, steroid hormones, contraceptives, cyclosporin), heavy alcohol drinker 3) Pregnancy 4) Patients under steroid hormone treatment 5) Unstable stage of the following diseases; coronary diseases, arrhythmias, valvular diseases, heart failure, cerebrovascular diseases, renal failure, diabetes mellitus with very poor control, neuro-muscular diseases, malignancy 6) Conditions when doctors assume inappropriate to enroll
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of hypothyroidism and/or subclinical hypothyroidism in patients with hyperlipidemia | — |
Secondary
| Measure | Time frame |
|---|---|
| Effects of thyroid hormone replacement on serum lipid levels | — |
Countries
Japan
Contacts
National Hospital Organization, Kyoto Medical Center Department of Endocrinology, Clinical Research Institute for Endocrine and Metabolic Diseases