Clinical trial of mesenchymal stem cell transplantation for severe heart failure

Clinical trial of mesenchymal stem cell transplantation for severe heart failure - Mesenchymal stem cell transplantation for severe heart failure

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000656

Enrollment

Registered

2007-04-01

Start date

2003-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe chronic heart failure

Interventions

11/1/2003-5/31/2009

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Heart failure (ejection fraction of less than 40%) due to old myocardial infarction, dilated cardiomyopathy and other causes, and refractory to other drug therapies such as ACE inhibitors, beta-blockers and diuretcs

Exclusion criteria

Exclusion criteria: 1. Any evidence of cancer or active infectious disease 2. Presence of proliferative diabetic retinopathy 3. Renal failure or hepatic failure 4. Any evidence for abnormality in peripheral blood 5. History of PTCA or CABG in the 6 months prior to study entry 6. History of acute myocardial infarctioin, unstable angina or myocarditis in the 6 months prior to study entry 7. Not pregnant 8. Presence of embolism in the left ventricle 9. Presence of aortic valve stenosis or aortic artificial valve 10. Very severe hear failure patients who can not endure invasive examination such as catheterization and bone marrow aspiration

Design outcomes

Primary

Measure	Time frame
Safety Ejection fraction	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026