Open-label, single-center, randomized and parallel-group study to compare the effect of Hydrofluoroalkane-134a beclomethasone dipropionate and Chlorofluorocarbon beclomethasone dipropionate on small airways involvement in asthma assessed using impulse oscillometry system.

Open-label, single-center, randomized and parallel-group study to compare the effect of Hydrofluoroalkane-134a beclomethasone dipropionate and Chlorofluorocarbon beclomethasone dipropionate on small airways involvement in asthma assessed using impulse oscillometry system. - Controlled study to compare the effect of Hydrofluoroalkane-134a beclomethasone dipropionate and Chlorofluorocarbon beclomethasone dipropionate in bronchial asthma.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000632

Enrollment

Registered

2007-03-09

Start date

2005-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial asthma

Interventions

Hydrofluoroalkane-134a beclomethasone dipropionate 200 mcg bids 12 weeks Chlorofluorocarbon dipropionate 400 mcg bid 12 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inhaled corticosteroids-naive mild-to-moderate asthmatic patients

Exclusion criteria

Exclusion criteria: 1 Current smoker 2 Past treatment with inhaled corticosteroids 3 Receiving oral corticosteroids in the previous 2 months

Design outcomes

Primary

Measure	Time frame
Parameters of impulse oscillometry system.	—

Secondary

Measure	Time frame
1 Symptoms 2 Wheezing on auscultation 3 Methacholine airway responsiveness 4 Pulmonary function 5 Lung volume measurement 6 Inflammatory biomarkers of induced sputum and peripheral blood 7 Safety	—

Countries

Japan

Contacts

Public ContactMasafumi Yamaguchi

Kyoto University Graduate School of Medicine Department of Respiratory Medicine

075-751-3830

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026