Second-line and third-line treatment after unsuccessful H. pylori eradication

Second-line and third-line treatment after unsuccessful H. pylori eradication - Second-line and third-line H. pylori eradication treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000578

Enrollment

300

Registered

2007-04-01

Start date

2004-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H. pylori infection

Interventions

Second-line regimen lansoprazole 60mg 2x amoxicillin 1500mg 2x metronidazole 750mg 2x (500-250) Third-line regimen rabeprazole 40mg 4x amoxicillin 2000mg 4x gatifloxacin 400mg 1x

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who had one or two treatment failures (first-line treatment used: triple therapy with PPI-AMX-CLR for 7 days; second-line treatment used; triple therapy with PPI-AMX-MNZ for 7 days)

Exclusion criteria

Exclusion criteria: allergy to drugs stated in protocol or pregnncy

Design outcomes

Primary

Measure	Time frame
eradication rate	—

Countries

Japan

Contacts

Public ContactToshihiro Nishizawa

Keio University School of Medicine Department of Internal Medicine

nisizawa@f7.so-net.ne.jp03-3353-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026