Randomized trial of transbronchial biopsy with or without navigation by virtual bronchoscopy using X-ray fluoroscopy and endobronchial ultrasonography with guide-sheath (BUS-GS) for pulmonary peripheral small lesions

Randomized trial of transbronchial biopsy with or without navigation by virtual bronchoscopy using X-ray fluoroscopy and endobronchial ultrasonography with guide-sheath (BUS-GS) for pulmonary peripheral small lesions - Randomized trial of transbronchial biopsy with or without navigation by virtual bronchoscopy for pulmonary peripheral small lesions

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000569

Enrollment

200

Registered

2006-12-29

Start date

2006-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary peripheral small lesions

Interventions

With navigation by virtual bronchoscopy Without navigation by virtual bronchoscopy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Pulmonary peripheral small lesions of &#8804; 20 mm deemed, but not determined, as lung cancer 2.Not visible by bronchoscopy 3.20 or more than 20 years of age 4.SpO2 90 or more than 90% 5.Written informed consent

Exclusion criteria

Exclusion criteria: 1.Visible by bronchoscopy 2.GGO 3.Lesions deemed as benign diseases on chest CT 4.Severe complication 5.Disability of cessation of anticoagulant or antiplatelet more than 2 days 6.Pregnancy

Design outcomes

Primary

Measure	Time frame
Yield (Diagnostic rate)	—

Secondary

Measure	Time frame
1)The time to reach the lesion 2)The time of first biopsy 3)The time of X-ray fluoroscopy 4)The time of total examination 5)Difference between bronchi by virtual bronchoscopy and actual bronchi 6)Bronchial generation inserted by bronchoscopy 7)Complication 8)Patient suffering by bronchoscopy	—

Countries

Japan

Contacts

Public ContactKoichi Yamazaki

Hokkaido University School of Medicine First Department of Medicine

kyamazak@med.hokudai.ac.jp011-706-5911

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026