Phase II trial of docetaxel and carboplatin in patients with stage IVb or recurrent nonsquamous cell carcinoma of uterine cervix

Phase II trial of docetaxel and carboplatin in patients with stage IVb or recurrent nonsquamous cell carcinoma of uterine cervix - Phase II trial of docetaxel and carboplatin in patients with stage IVb or recurrent nonsquamous cell carcinoma of uterine cervix

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000564

Enrollment

Registered

2007-01-01

Start date

2006-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nonsquamous cell carcinoma of uterine cervix

Interventions

Patients with stage IVb recurrent nonsquamous cell carcinoma of uterine cervix

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1.Patients having measurable lesions with definite histopathological diagnosis of stage IVb or recurrent nonsquamous cell carcinoma of uterine cervix 2.Recurrent patients can received any prior treatment including chemotherapy or radiotherapy as far as having interval more than 4 weeks. Concurrent combination radiotherapy can not be permitted. 3.Performance status: 0-2 4.Age: 20-75 years old 5.Patients without severe dysfunction of major organs 6.Patients can be alive over 3 moths after treatment 7.Patients must have signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Fever with over 38.0C 2.Infection or WBC>12,000/mm3 3.Severe complications 4.Neuropathy >Grade 2 5.Edema > Grade 2 6.Double cancer 7.Massive pleural effusion and ascites 8.Hypersensitivity reactions to docetaxel or carboplatin 9.Patients judged as exclusive case by the investigator

Design outcomes

Primary

Measure	Time frame
Efficacy	—

Secondary

Measure	Time frame
Safety, Overall survival	—

Countries

Japan

Contacts

Public ContactMuneaki Shimada

Tottori University Department of Obstetrics and Gynecology

mshima12@med.tottori-u.ac.jp0859-38-6647

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026