pediatric renal transplantation
Conditions
Interventions
Mycophenolate mofetil
Sponsors
Japanese Study group of Pediatric Renal Transplantation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Recipients of a first kidney allograft from a living or cadaver donor 2. Patients under the age of 20 3.Written informed consent from the patients' parents or legal guardians 4. Patients who are able to go to hospital during therapy of the trial
Exclusion criteria
Exclusion criteria: 1. The acute rejection after renal transplantation. 2. Use ofimmunosuppressant which works the same way as MMF does. 3. Prior exposure to live vaccine within one month before the treatment of MMF 4. Active peptic ulcer disease 5. Severe liver dysfunction 6. Leucopenia at study entry 7. Active systemic infection 8. Malignancy 9. Hemorrhagic diathesis 10. Refractory diarrhea 11. Medical history of severe allergy or drug hypersensitivity 12. ABO-incompatible kidney allograft 13. Anti-donor antibody positive patients 14. Pregnancy 15. Judged inappropriate for this study by the physicians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the proportion of patients experiencing a rejection episode within the first 6 months post-transplantation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.the proportion of patients who kept their graft by 12 months post-transplantation. 2.the proportion of patients who lived at 12 months post-transplantation. 3.the proportion of patients experiencing a biopsy-proven rejection episode at 12 months post-transplantation. | — |
Countries
Japan
Contacts
Public ContactMayumi Sako
National Center for Child Health and Development Department of Nephrology
Outcome results
None listed