osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: healthy premenopausal female
Exclusion criteria
Exclusion criteria: Medication of steroid hormone (corticosteroids, estrogen), Metabolic diseases related to calcium turnover (hyper and hypothyroidism, hyper and hypo-parathyroidism etc) Unable to complete 1 year intervention and examination Pregnant Within 1 year of delivery Within 6 month of breast feeding Ovariectomized Diagnosed as osteoporosis Patients with severe diseases such as cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density as assessed by DXA (lumbar spine L1-4, left femoral neck and trochanter), and by QUS(calcaneus) | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone metabolism marker: cross-linked N. telopetide of type I Collagen(NTX); bone alkaline phosphatase(BAP) | — |
Countries
Japan
Contacts
Tohoku University Graduate School of Medicine Department of Medicine and Science in Sports and Exercise