Effects of sivelestat sodium in acute respiratory failure caused by sever pneumonia

Effects of sivelestat sodium in acute respiratory failure caused by sever pneumonia - Effects of sivelestat sodium in acute respiratory failure caused by sever pneumonia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000000524

Enrollment

Registered

2006-11-17

Start date

2006-11-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory failure caused by sever pneumonia

Interventions

Control (usual therapy) group: Initial antibiotic administration following the JRS/ATS/IDSA guidelines, and later adjusted to the results of bacterial culture results and antibiogram. Non invasive po

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Sever pneumonia and acute respiratory failure receiving NPPV

Exclusion criteria

Exclusion criteria: Respiratory arrest, respiratory pause with loss of consciousness, sever hemodynamic instability

Design outcomes

Primary

Measure	Time frame
Duration of ventilatiory assistance, need for endotracheal intubation and mechanical ventilation	—

Secondary

Measure	Time frame
PaO2/FiO2 ratio, in-hospital survival	—

Countries

Japan

Contacts

Public ContactSeiichi Kobayashi

Ishinomaki Red Cross Hospital Department of Respiratory Medicine

skoba-thk@umin.ac.jp0225-21-7220

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026