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Impact of inflammation, oxidative stress and anti-vascular calcification factors on progress of atherosclerosis in end-stage renal disease patients

Impact of inflammation, oxidative stress and anti-vascular calcification factors on progress of atherosclerosis in end-stage renal disease patients - Study for atherosclerosis-associated factors in end-stage renal disease patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000000491
Enrollment
500
Registered
2006-09-19
Start date
2006-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage renal disease

Interventions

None listed

Sponsors

Division of Nephrology Department of Medicine Showa University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Renal dysfunction: end-stage chronic kidney disease, require maintenance dialysis due to renal dysfunction 2) Expected survival time is more than 6 months 3) Aged 20 years over 4) Fully informed consent was obtained

Exclusion criteria

Exclusion criteria: 1) Malignancy 2) Malnutrition 3) Active inflammatory or infectious disease 4)) Abdominal ascites or pleural effusion 5) Pregnancy 6) Judged inappropriate for this study by the physicians

Design outcomes

Primary

MeasureTime frame
In the cross-sectional and prospective studies (n=600), impact of inflammation, oxidative stress vascular calcification associated factors on atherosclerosis progress.

Secondary

MeasureTime frame
Assessment of nutritional state and factors which associated with atherosclerosis

Countries

Japan

Contacts

Public ContactHirokazu Honda

Showa University School of Medicine Division of Nephrology Department of Medicine

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026