Expression profiling of clinical stage II/III esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy.

Expression profiling of clinical stage II/III esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy. - Expression profiling of esophageal carcinima patients treated with definitive chemoradiotherapy.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-C000000459

Enrollment

120

Registered

2006-08-01

Start date

2005-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

clinical stage II/III esophagel squamous cell carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients with untreated thoracic esophageal cancer (2) Historical confirmation of squamous cell carcinoma from primary tumor (3) Cinical stage II and III(excluding of T1 and T4)(UICC2002) (4) Age 20 to 75 (5) Performance status(ECOG):0-1 (6) Adequate organ functions for definitive chemoradiotherapy (7) No prior therapy for other malignancies with chemotherapy, radiotherapy and genetic treatment. (8) No other active malignancies (9) Written informed consent

Exclusion criteria

Exclusion criteria: (1) Tumor invasive to the cervical esophagus or gastric cardia with endoscope (2) Patients who have infectionous disease (type B and C hepatitis virus, human immunodeficiency virus, syphilis) and their carrier (3) Patients who are suffered infection and inflammation (4) No other severe medical conditions and patients who are pregnant or breast-feeding (5) Any other inappropriate state for participating to this study estimated by physician

Design outcomes

Primary

Measure	Time frame
Find the gene expression patterns and make programs which predict efficacy of definitive CRT and confirm its accuracy.	—

Countries

Japan

Contacts

Public ContactKeiko Minashi

National cancer center hospital east Department of gastroenterology and GI oncology

04-7133-1111

Outcome results